Prescribing Information

Prescribing Information for E45 Cream 

Name: E45 Cream

Active Ingredient: White Soft Paraffin 14.5% w/w, Light Liquid Paraffin 12.6% w/w and Anhydrous Lanolin 1.0% w/w.

Indications:  For the symptomatic relief of dry skin conditions, where the use of an emollient is indicated, such as flaking, chapped skin, ichthyosis, traumatic dermatitis, sunburn, the dry stage of eczema and certain dry cases of psoriasis.

Dosage and administration:  Adults, children, infants over 1 month and the elderly:  Apply to the affected part two or three times daily.

Contra-indications:  E45 Cream should not be used by patients who are hypersensitive to white soft paraffin, liquid light paraffin and anhydrous lanolin or any of the excipients.  

Precautions and Warnings: If a rash develops, use of the product should be discontinued. Patients being dispensed or treated with large quantities (> 100g) of any paraffin - based product should be advised to regularly change clothing, bedding or dressings impregnated with the product and keep away from naked flames as there is a fire hazard.

Fertility, Pregnancy and Lactation: No effects during pregnancy are anticipated, since systemic exposure to white soft paraffin, liquid paraffin and lanolin is negligible. As with all medicines, this product should be used with caution during pregnancy. It is unknown whether soft paraffin, light liquid paraffin and anhydrous lanolin metabolites are excreted in human milk. A risk to the newborns/ infants cannot be excluded. Application of the product to the breast is not recommended during breast feeding. No data on human fertility are available.

Side effects:  Occasionally, hypersensitivity reactions, otherwise adverse effects are unlikely.  Should this occur, use of the product should be discontinued. For full information on adverse reactions see SPC.

Product licence number:  PL 00063/0404

Product licence holder:  Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 4AQ, UK

Legal category:  GSL

MRRP:   £2.49 50g, £4.49 125g, £7.99 350g, £9.99 500g (excl VAT)

NHS list price:
   £1.61 50g, £2.91 125g, £5.17 350g, £5.62 500g (excl VAT)

Date of preparation:  November 2016 - For full information refer to SPC (https://www.medicines.org.uk/emc/medicine/21988)


Adverse events should be reported. Reporting forms can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Reckitt Benckiser (0333 2005 345)


Prescribing Information for E45 Itch Relief Cream 

Name: E45 Itch Relief Cream

Active Ingredients: Lauromacrogols 3.0% w/w and Urea 5.0%w/w.

Indications: For the treatment of pruritus, eczema, dermatitis and scaling skin conditions where an antipruritic and/or hydrating effect is required.  It may also be used for the continued treatment and follow-up treatment of these skin diseases.

Dosage and administration:  Adults, the elderly, children and infants over 1 month:  Apply to each affected area twice a day.  The duration of treatment depends on the clinical response.  

Contra-indications:  Patients with known hypersensitivity to any of the ingredients.  It should not be used to treat acute erythroderma, acute inflammatory, oozing or infected skin lesions.

Precautions and Warnings:  May cause irritation if applied to broken or inflamed skin.  

Pregnancy and lactation:  There are no specific restrictions concerning its use during pregnancy, but it is not to be used on the breasts immediately prior to breast feeding during lactation.

Side effects:  E45 Itch Relief Cream has been reported to cause a burning sensation, erythema, pruritus or the formation of pustules.  Contact allergy has also been reported.

Product licence number:  PL 00327/0122

Product licence holder:  Crookes Healthcare Ltd, Nottingham, NG2 3AA, UK

Legal category:  GSL

MRRP:  £4.49 50g, £5.99 100g and £24.45 500g (excl VAT)

NHS list price:  £2.55 50g, £3.47 100g and £14.99 500g (excl VAT)

Date of preparation:  November 2016. For full information refer to SPC (https://www.medicines.org.uk/emc/medicine/20039)


Adverse events should be reported. Reporting forms can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Reckitt Benckiser (0333 2005 345)

 

Prescribing Information Hc45 Hydrocortisone Cream 

Name: Hc45 Hydrocortisone Cream

Active ingredient:  Hydrocortisone acetate BP 1.0% w/w.

Indications:  For the treatment of irritant contact dermatitis, allergic contact dermatitis, insect bite reactions and mild to moderate eczema. 

Dosage and administration:  For topical administration.  Apply accurately and sparingly to a small area, once or twice a day, for a maximum of 7 days.  If the condition is not improved, consult your doctor.  Do not use in children under 10 years without medical advice.

Contra-indications:  Hc45 Hydrocortisone Cream should not be used by patients who are hypersensitive to hydrocortisone acetate or to any other excipients. The product should not be used on the eyes or face (for example, in rosacea or perioral dermatoses), the ano-genital area or on broken or infected skin including impetigo, cold sores, acne athlete’s foot, or infected bites and stings.  The product should not be used in the presence of untreated infections of bacterial, viral, tuberculous or fungal origin. Not for use with an occlusive dressing or on large areas of the body.

Precautions and Warnings:.  If the condition does not improve consult your doctor. Prolonged use of the product is not recommended. Contains: Cetomacrogol emulsifying wax with Cetostearyl Alcohol, which may cause local skin reactions (e.g. contact dermatitis).

Fertility, Pregnancy and Lactation:  Do not use in pregnancy or when breast-feeding unless recommended by a healthcare professional .  There are no or limited amount of data from the use of topical corticosteroids in pregnant women. Studies in animals have shown reproductive toxicity.   Corticosteroids are excreted in human milk. There is no information about effects on lactation.  A risk to new-borns/infants cannot be excluded.  No known effects on Fertility

Side effects:  If any signs of hypersensitivity, including allergic contact dermatitis or worsening of the original condition appear, treatment should be immediately discontinued.  For full information on adverse reactions see SPC.

Product licence number:  PL 00063/0647

Product Licence holder:  Reckitt Benckiser Healthcare (UK) Ltd, Slough, SL1 4AQ

Legal category:  P

MRRP: £3.99 15g (excl VAT) 
NHS list price:  £2.58 15g (excl VAT) 

Date of preparation:  July 2017 – For full information refer to SPC (https://www.medicines.org.uk/emc/medicine/23417)


Adverse events should be reported. Reporting forms can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Reckitt Benckiser (0333 2005 345)